Check out this article that details a “Crisis Management App” that first responders in Marietta, Georgia use in emergencies. The application, developed with ESRI’s ArcView 10 and Adobe Flex, is designed to be used by non-GIS experts. Although it is designed for easy functionality, the capabilities of the application remain rich. Users (first responders) can add features, such as incidents and roadblocks in addition to accessing imagery and live video stream.
Also, be sure to check out this CNN article that details the growing use of Social Media in times of disaster. Russ Johnson, the director for public safety and homeland security for ESRI, is quoted throughout the article describing how these tools can help emergency resources be deployed more efficiently in time sensitive situations.